Recently, interest in two-dimensional nanomaterials such as graphene or transition metal dichalcogenide is rapidly increasing in order to overcome the limitations of traditional materials and find new applications. The high surface area of 2D nanomaterials and the layered structure conducive to ion transport can be used as electrode materials in electrochemical energy storage applications, and the atomic-level thickness can enable inorganic flexible optoelectronic devices. In this presentation, the applications of 2D nanomaterials such as energy devices and optoelectronic devices and the process of finding new physics about defects that enable a quality analysis of 2D materials through Tip-Enhanced Raman Scattering and AI spectroscopy will be introduced.