Efficient tungsten carbide (W₂C) nanoparticles were successfully prepared via a facile chemical reduction
method. Structural confirmation studies were performed using spectroscopy and microscopy studies. The dropcasted
W₂C nanoparticles on glassy carbon electrode (GCE) used for the fabrication of molecularly imprinted
polymer (MIP) using oxalic acid (OA) in the presence of dopamine as a functional monomer through selfpolymerization.
For the first time, fabricated MIP-W₂C/GCE sensor used for the electrochemical detection of OA,
a reliable kidney stone marker. The different loading mass of W₂C nanoparticles and thickness of MIP layer were
used to investigate its electrochemical activity towards the OA sensor. The developed MIP-W2C/GCE sensor
operated in an extensive concentration level of 0.1 nM−100 μM, and it offered an LOD of 0.04 nM with an
excellent regression coefficient of 0.998, good reproducibility which proved from the four different sensors (RSD
− 2.8%), and retained nearly 94% of its initial activity even after 35 days. The prepared sensor also successfully
demonstrated its capability to detect OA in the real urine samples with the recovery range of 98.03–100.24 %.